Music from DNA: Creating a SinFonia inside a bacterial cell

PRESS RELEASE If you could listen to the DNA in your genes, how would it sound like? This question stood at the beginning of the groundbreaking collaboration between a musical composer and a microbiologist, and the answer to that question is now online and available to the public. Eduardo Miranda, a composer from the University of Plymouth, UK, worked with…

New Publication in Nature Communications by Loschmidt Laboratories

The research on protein dynamics of our project partners Loschmidt Laboratories (Department of Experimental Biology and RECETOX, Faculty of Science, Masaryk University) and International Clinical Research Center, St. Anne’s University Hospital Brno has been published in the prestigious journal Nature Communications. Below is a short summary to give you an overview. You can access the full article on Nature Communications.…

2nd Hands-on Computational Enzyme Design Course

The Hands-on Computational Enzyme Design Course is a highly practical and interactive course meant primarily for protein and metabolic engineers with no prior experience in computer modelling and bioinformatics. Other experts willing to broaden their current computational protein design toolbox can also benefit from this course. A team of experts and software developers provide training on how to operate several…

Protein Engineering Portal by Loschmidt Laboratories

Loschmidt Laboratories of Masaryk University has launched a Protein Engineering Portal. The portal serves as a gateway to several web-based bioinformatics tools. The software tools can be used for designing proteins, analysis and research.  Have a look at the portal and browse through the various useful tools such as EnzymeMiner, FireProt or Caver Web.

Our artist in residence has been revealed!

Biofaction organized an open call for our new Artist in Residence programm. The call received 166 submissions from 43 countries in total and around 30 submissions for SinFonia. The jury panel had the difficult task of selecting one artist for SinFonia among many interesting choices. We congratulate the winning artist Eduardo Miranda. He will be working at the Novo Nordisk Foundation Center for Biosustainability, Technical University…

New Bioinformatics Software Tool SoluProt by Loschmidt Laboratories

Our project partner Masaryk University has developed another bioinformatics software tool called SoluProt in their Loschmidt Laboratories research group.It is a tool for prediction of soluble protein expression in Escherichia coli. Obtaining soluble proteins in sufficient amounts is a recurring limiting factor in various experimental studies as well as in industrial productions. Many valuable protein molecules suffer from poor solubility and…

Call for Artists

We are looking for artists who want to take part in our Artist in Residence programme at the Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark. Musicians and composers are especially welcome to apply for this programme. The selected artist will actively engage with Sinfonia scientists and delve into the fascinating area of cell factories for four to six weeks.  Here are some…

New Bioinformatics Tool EnzymeMiner by Loschmidt Laboratories

Our project partner Masaryk University has developed a new bioinformatics tool called EnzymeMiner in their Loschmidt Laboratories research group, in order to address time-demanding and cost-ineffective classical biochemical characterization techniques. EnzymeMiner is a web server for automated screening of diverse family members and selection of representative hits for experimental characterization of enzymes. EnzymeMiner is a universal tool that is applicable to any enzyme…

New Version of CAVER PyMOL Plugin

The Loschmidt Laboratories programming team is happy to announce a new version of the CAVER PyMOL plugin. CAVER is a software tool for the analysis and visualization of tunnels and channels in protein structures. The new plugin version is now compatible also with PyMOL version 3.0 and has multiple improvements to make its installation and usage easier. For more information…